← Landau Lab

Site information

Visual sources

The homepage uses a three-part ambient sequence spanning MRI, genetics, and laboratory automation. The clips are muted, color-graded consistently, and shown with motion and data-saving fallbacks.

Licence

The Landau Lab’s own text and original graphics, animations and diagrams on this website are © Landau Lab and licensed under Creative Commons Attribution 4.0 International (CC BY 4.0). You may share and adapt them, including commercially, if you credit the Landau Lab and link to the licence.

Not covered (these keep their own terms, as listed on this page and where they appear):

  1. 01

    A modern MRI machine

    MART PRODUCTION · Pexels video 7088517

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  2. 02

    Abstract DNA helix in blue tones

    Nicola Narracci · Pexels video 27650713

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  3. 03

    Automated liquid handling

    Thirdman · Pexels video 8940765

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Published figures

Research pages reproduce figures from the lab's papers. Most are used under their Creative Commons licences; a few (items 14–16) are reused by the authors under the publisher's terms and are not Creative Commons. Each figure is credited in place; the list below collects them.

  1. 04

    [11C]UCB-J PET in the rat (whole figure)

    Binda KH, Real CC, Simonsen MT, Grove EK, Bender D, Gjedde A, Brooks DJ, Landau AM. Psychophysiology 2025;62:e14709 · Figure 3 · CC BY-NC-ND 4.0, reproduced unmodified · used on Tracer studio and Research › Brain stimulation

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  2. 05

    What can altered SV2A binding represent?

    Rossi R, Arjmand S, Bærentzen SL, Gjedde A, Landau AM. Frontiers in Neuroscience 2022;16:864514 · Figure 2 · CC BY 4.0; panel labels added · used on the homepage, Tracer studio and Research › Synaptic imaging

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  3. 06

    [11C]yohimbine VT maps in the minipig

    Landau AM, Jakobsen S, Thomsen MB, Alstrup AKO, Orlowski D, Jacobsen J, Wegener G, Mørk A, Sørensen JCH, Doudet DJ. Biomolecules 2023;13:674 · Figure 3 (panels a and b) · CC BY 4.0; cropped · used on Methods and in the lab film

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  4. 07

    [3H]UCB-J autoradiography in rats

    Binda KH, Lillethorup TP, Real CC, Bærentzen SL, Nielsen MN, Orlowski D, Brooks DJ, Chacur M, Landau AM. Experimental Neurology 2021;342:113741 · Figure 4A · CC BY 4.0; cropped · used on the homepage (selected findings, beside Figure 3A), Methods, Research › Synaptic imaging and in the lab film

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  5. 08

    [3H]PK11195 autoradiography of TSPO in rats

    Binda KH, Lillethorup TP, Real CC, Bærentzen SL, Nielsen MN, Orlowski D, Brooks DJ, Chacur M, Landau AM. Experimental Neurology 2021;342:113741 · Figure 3A · CC BY 4.0; cropped, panel letter removed · used on the homepage (selected findings, beside Figure 4A) and on Research › Neuroinflammation, where a highlight and shading added by us step through the four sections

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  6. 09

    [3H]UCB-J autoradiography of minipig prefrontal cortex

    Bærentzen SL, Thomsen MB, Alstrup AKO, Wegener G, Brooks DJ, Winterdahl M, Landau AM. Neuropharmacology 2024;256:110018 · Figure 2 (autoradiograms) · CC BY 4.0; cropped · used on Methods

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  7. 10

    Seeing Chemistry — PET in Psychiatry (poster frame)

    Landau Lab teaching video · teaching.landaulab.net · linked from Tracer studio

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  8. 11

    [11C]carfentanil and [11C]raclopride PET in minipigs, before and after sucrose

    Winterdahl M, Noer O, Orlowski D, Schacht AC, Jakobsen S, Alstrup AKO, Gjedde A, Landau AM. Scientific Reports 2019;9:16918 · Figure 1 · CC BY 4.0; unmodified · used in the lab film

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  9. 12

    Close-up of a microscope

    Mikhail Nilov · Pexels video 9430414 · colour-graded · used in the lab film

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  10. 13

    Real-time autoradiography loops (homepage background)

    "Inside the gap" and "Slides in real time": animations of the BeaQuant detector and of sections forming count by count. Counts are simulated, placed by binding recovered from real BeaQuant autoradiograms in Krogsbaek M, Larsen NY, Landau AM, Sanchez C, Nyengaard JR. Journal of Chemical Neuroanatomy 2023;132:102324, Fig. 3 · CC BY 4.0; cropped, labels removed, recoloured. Detector geometry after Donnard et al. 2009 and Delayre et al. 2020 (layout reference only, not to scale). The other homepage background clips are an illustrative PET-ring animation and stock video.

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  11. 14

    [11C]UCB-J PET in the minipig, at baseline and after levetiracetam

    Thomsen MB, Schacht AC, Alstrup AKO, Jacobsen J, Lillethorup TP, Bærentzen SL, Noer O, Orlowski D, Elfving B, Müller HK, Brooks DJ, Landau AM. Preclinical PET studies of [11C]UCB-J binding in minipig brain. Molecular Imaging and Biology 2020;22(5):1290–1300 · Figure 1 (panels a and b) · First published in Molecular Imaging and Biology, 22, 1290–1300, 2020 by Springer Nature · © 2020 World Molecular Imaging Society · reused by the authors; cropped and resized only; not CC-licensed · used in the PET-versus-autoradiography film on Methods › Real-time autoradiography

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  12. 15

    [3H]UCB-J autoradiography of the minipig brain, with levetiracetam block

    Thomsen MB, Schacht AC, Alstrup AKO, Jacobsen J, Lillethorup TP, Bærentzen SL, Noer O, Orlowski D, Elfving B, Müller HK, Brooks DJ, Landau AM. Preclinical PET studies of [11C]UCB-J binding in minipig brain. Molecular Imaging and Biology 2020;22(5):1290–1300 · Figure 4 (panels a and b) · First published in Molecular Imaging and Biology, 22, 1290–1300, 2020 by Springer Nature · © 2020 World Molecular Imaging Society · reused by the authors; cropped and resized only; not CC-licensed · panel a shown as a figure, and panels a and b used in the PET-versus-autoradiography film, on Methods › Real-time autoradiography; the top row of panel a, cropped into its three columns and shown one at a time, on Research › Synaptic imaging

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  13. 16

    [11C]UCB-J PET in the rat, at baseline and after levetiracetam

    Thomsen MB, Jacobsen J, Lillethorup TP, Schacht AC, Simonsen M, Romero-Ramos M, Brooks DJ, Landau AM. In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET. Journal of Cerebral Blood Flow & Metabolism 2021;41(4):819–830. Copyright © 2020 The Author(s), published by SAGE · Figure 1 (panels A and B) · from the authors' submitted manuscript (the figure file supplied by the authors), which SAGE allows authors to share after acceptance; reproduced unmodified; not CC-licensed, and free to view but not offered for reuse · used on the homepage (stop 03, "When two methods agree"), on Tracer studio and on Research › Synaptic imaging

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  14. 17

    Team portraits

    Photographs supplied by each lab member for the website and shown with their consent · cropped to one shape and gently toned for the site; metadata removed · not CC-licensed · used on People and on the homepage (stop 05)

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  15. 18

    [18F]GE-179 PET in the minipig, before and during deep brain stimulation

    Vibholm AK, Landau AM, Alstrup AKO, Jacobsen J, Vang K, Munk OL, et al., Brooks DJ. Activation of NMDA receptor ion channels by deep brain stimulation in the pig visualised with [18F]GE-179 PET. Brain Stimulation 2020;13(4):1071–1078 · Figure 4 · CC BY-NC-ND 4.0, reproduced unmodified · used on Research › Brain stimulation

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  16. 19

    [3H]PK11195 autoradiography of TSPO in α-synuclein and control rats

    Stokholm K, Thomsen MB, Phan JA, Møller LK, Bay-Richter C, Christiansen SH, Woldbye DPD, Romero-Ramos M, Landau AM. Biomedicines 2021;9(12):1876 · Figure 7 · CC BY 4.0; resized · used on Research › Neuroinflammation

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  17. 20

    Protein structures in the GPR6 film (homepage, theme 01)

    Rendered by us from atomic coordinates in the RCSB Protein Data Bank. GPR6 with the G protein Gs: PDB 8TYW (cryo-EM); GPR6 with CVN424: PDB 8T1W (crystal structure; the fusion protein used for crystallisation removed); both Barekatain M, Johansson LC, Lam JH, et al., Cherezov V. Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson's disease. Science Signaling 2024;17:eado8741. The receptor changes between these two measured structures. The Gαs helical domain, not modelled in 8TYW, is taken from PDB 3SN6 (Rasmussen SGF et al. Nature 2011;477:549–555), which also gave the membrane orientation. The Gαs subunit that travels from GPR6 to the cyclase changes between its receptor-bound structure (8TYW, with 3SN6) and its GTPγS-bound structure on the cyclase: adenylyl cyclase 9 with activated Gαs, PDB 6R3Q, with the active site located from 6R4O (Qi C, Sorrentino S, Medalia O, Korkhov VM. Science 2019;364:389–394); striatal neurons mainly use adenylyl cyclase 5, for which this structure stands in. Membrane orientations from the OPM database (Lomize MA et al. Nucleic Acids Research 2012;40:D370–D376). Small molecules (CVN424, cAMP) from the PDB Chemical Component Dictionary. The lipid bilayer is built procedurally; the timing of the relay, rates and amounts are illustrative.

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  18. 21

    Gpr6 in situ hybridization in the mouse brain (homepage, theme 01)

    Allen Mouse Brain Atlas, experiment 71247615 (coronal, probe RP_050331_02_H09), section image 71115363 · Image credit: Allen Institute · Allen Institute (2004). Allen Mouse Brain Atlas [dataset], mouse.brain-map.org · Lein ES et al. Genome-wide atlas of gene expression in the adult mouse brain. Nature 2007;445:168–176 · recoloured (tissue darkened; the in situ signal and Allen's expression mask drawn as a glow)

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  19. 22

    Striatal medium spiny neuron reconstructions (homepage, theme 01)

    NeuroMorpho.Org (RRID:SCR_002145; Tecuatl C, Ljungquist B, Ascoli GA. FASEB BioAdvances 2024;6:207–221; Ascoli GA et al. J Neurosci 2007;27:9247–9251), NMO_101622–101649, from Goodliffe JW et al. Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington's disease. PLoS One 2018;13:e0200626 (wild-type control cells only) · CC BY 4.0 · depth stretched to offset slice shrinkage; dendritic spines and axons added for illustration

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  20. 23

    The BeaQuant instrument (photos)

    Photos: Landau Lab, 2026 · the BeaQuant real-time autoradiography system (ai4R) at the Department of Nuclear Medicine, used by the Landau Lab · cropped to the instrument and exposure gently lifted; not recoloured or retouched; metadata removed · not CC-licensed · used on Methods › Real-time autoradiography

    BeaQuant page →