Translational Neuroimaging · Aarhus University
We use molecular brain imaging to find new therapeutic targets and biomarkers for psychiatric and neurodegenerative disease — tracking how brain circuits respond to disease and therapy, from rodents to large animals.
01 Research
Three research priorities, supported by a shared molecular-imaging toolkit that spans PET tracers, MRI, disease models, and tissue analysis — carried from tracer and model through to translational read-out.
We investigate GPR6, a receptor on dopamine-signalling neurons, as a novel therapeutic target in depression — using the GPR6-targeting drug CVN424 to probe striatal circuits and behaviour. Supported by a Lundbeck Foundation Ascending Investigator Grant.
We use SV2A / [¹¹C]UCB-J PET to image synaptic change in disease models and in response to therapies — including deep brain stimulation, exercise, and S-ketamine.
We develop imaging biomarkers of neuroinflammation across neurodegenerative and psychiatric disease, turning the brain's immune response into a measurable read-out.
We run molecular imaging in rodent, transgenic-mouse, and large-animal (Göttingen minipig) models, pairing PET with MRI, behaviour, and tissue analysis to carry findings from the bench toward the clinic.
02 Approach
Careful measurement first; interpretation that stays close to the data.
The Landau Lab develops and validates molecular brain imaging to track how neural circuits adapt across disease, injury, and therapy. We pair PET with MRI, behaviour, and tissue analysis, working across rodent, large-animal, and genetic models.
Our aim is consistent and translational: read-outs that can move from the bench toward the clinic. Much of the work is collaborative — spanning groups and institutions — and a good deal of it is carried out by students and early-career researchers within the group.
03 People
Led by the principal investigator, with a team of researchers, students, and clinicians.
Associate Professor & Principal Investigator
Translational Neuropsychiatry Unit · Aarhus University, Denmark
Anne leads the Landau Lab, developing molecular brain imaging — PET and MRI — to find new therapeutic targets and biomarkers for psychiatric and neurodegenerative disease, and to track how brain circuits respond to disease and therapy across species.
Group members, selected projects, and individual profiles are in preparation. In the meantime, prospective students and collaborators are warmly encouraged to get in touch.
Join the lab. We welcome enquiries from prospective PhD students, postdocs, and project students with an interest in molecular imaging, neuroscience, and translational research.
Get in touch04 Publications
A reverse-chronological selection of recent peer-reviewed publications from the group and its collaborations.
For the full, up-to-date publication list, see Anne M. Landau's profile at Aarhus University ↗.
05 Contact
For collaboration, prospective positions, or general enquiries about our imaging work, we would be glad to hear from you.
alandau@clin.au.dk